Description

Methyl 2,6-Difluoro-3,5-Dimethoxybenzoate is a high-purity fluorinated aromatic ester building block of significant interest in advanced organic synthesis. Its core value lies in its unique substitution pattern, which provides a versatile and reactive scaffold for constructing complex molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly those requiring difluoromethoxy or difluorinated aromatic motifs.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for introducing fluorinated aromatic systems which can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the difluoro-dimethoxy benzoate structure contributes to biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes.
• Advanced Polymer Monomer: Employed in the synthesis of specialty polymers with tailored properties such as chemical resistance, thermal stability, and specific optical characteristics.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for methodology development and exploring new chemical spaces in fluoroorganic chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a commercial scale.

Basic Information

Item	Detail
Product Name	Methyl 2,6-Difluoro-3,5-Dimethoxybenzoate
CAS No.	651734-55-3
Molecular Formula	C10H10F2O4
Molecular Weight	232.18 g/mol
Synonyms	2,6-Difluoro-3,5-dimethoxybenzoic acid methyl ester; Methyl 2,6-difluoro-3,5-dimethoxybenzoate; Benzoic acid, 2,6-difluoro-3,5-dimethoxy-, methyl ester; 3,5-Dimethoxy-2,6-difluorobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 2,6-Difluoro-3,5-Dimethoxybenzoate adheres to stringent quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. All materials are analyzed using advanced techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.