Description

2-([4-(tert-Butoxycarbonyl)Piperazino]Carbonyl)Benzoic Acid is a high-purity, advanced pharmaceutical intermediate featuring a protected piperazine moiety. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of receptor-targeted therapies. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and process optimization for scale-up production.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting neurological and oncological pathways.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) requiring a protected piperazine carboxylic acid derivative.
• Peptidomimetic Research: Serves as a crucial component in the design and construction of peptidomimetics and other bioactive molecules.
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme function and receptor-ligand interactions.
• Process Chemistry & Scale-Up: Provides a reliable and high-quality starting material for process research and development (PR&D) and commercial manufacturing.

Basic Information

Product Name	2-([4-(tert-Butoxycarbonyl)Piperazino]Carbonyl)Benzoic Acid
CAS No.	651293-35-5
Molecular Formula	C₁₇H₂₂N₂O₅
Molecular Weight	334.37 g/mol
Synonyms	2-({4-[(2-Methylpropan-2-yl)oxycarbonyl]piperazin-1-yl}carbonyl)benzoic acid; 2-[(4-Boc-piperazinyl)carbonyl]benzoic acid; 2-(4-Boc-piperazine-1-carbonyl)benzoic acid; Benzoic acid, 2-[[4-[(1,1-dimethylethoxy)carbonyl]-1-piperazinyl]carbonyl]-; 2-(4-(tert-Butoxycarbonyl)piperazine-1-carbonyl)benzoic acid
EINECS	Contact for details

Quality Control

Our 2-([4-(tert-Butoxycarbonyl)Piperazino]Carbonyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.