Description

(R)-1-[(S)-2-[Di(2-Furyl)Phosphino]Ferrocenyl]Ethyldi(3,5-Xylyl)Phosphine is a highly specialized, chiral ferrocenyl phosphine ligand, a key component in asymmetric catalysis. Its value lies in its ability to induce high enantioselectivity in transition metal-catalyzed reactions, which is critical for producing single-enantiomer compounds. This ligand is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control for synthesizing advanced intermediates and active ingredients.

Application

• Asymmetric Hydrogenation: A premier ligand for the enantioselective reduction of prochiral olefins, ketones, and imines, crucial for producing chiral alcohols and amines in pharmaceutical synthesis.
• Asymmetric C-C Bond Formation: Employed in cross-coupling reactions, allylic substitutions, and other C-C bond-forming processes to create complex, chiral molecular architectures.
• Pharmaceutical Intermediate Synthesis: Used in the development and scale-up of chiral active pharmaceutical ingredients (APIs) and key synthetic intermediates.
• Agrochemical Manufacturing: Facilitates the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical and Specialty Chemical Production: Enables the synthesis of high-value chiral flavors, fragrances, and advanced materials.
• Catalyst Screening and Development: A valuable tool in academic and industrial research for discovering new catalytic systems and optimizing reaction conditions.

Basic Information

Product Name	(R)-1-[(S)-2-[Di(2-Furyl)Phosphino]Ferrocenyl]Ethyldi(3,5-Xylyl)Phosphine
CAS No.	649559-66-0
Molecular Formula	C41H37FeO2P2
Molecular Weight	670.52 g/mol
Synonyms	(R)-1-[(S)-2-(Di-2-furanylphosphino)ferrocenyl]ethyldi(3,5-xylyl)phosphine; Josiphos SL-J009-1; SL-J009-1; (R)-(S)-Josiphos; (R)-1-[(S)-2-(Diferrocenylphosphino)ferrocenyl]ethyldi(3,5-dimethylphenyl)phosphine (common misnomer); (R)-1-[(S)-2-(Di-2-furylphosphino)ferrocenyl]ethyldi(3,5-dimethylphenyl)phosphine; Chiral Josiphos-type ligand; FERRIPHOS.
EINECS	Contact for details

Quality Control

Every batch of (R)-1-[(S)-2-[Di(2-Furyl)Phosphino]Ferrocenyl]Ethyldi(3,5-Xylyl)Phosphine is produced and tested under strict quality management systems. We ensure high chemical and chiral purity through comprehensive analytical techniques including NMR, HPLC, and elemental analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and enantiomeric excess to meet your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C or as specified on the label or COA. This compound is easily oxidized; prolonged exposure to air should be avoided. Keep the container in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	Orange to red-brown solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity	≥ 99.0% ee
Solubility	Soluble in common organic solvents (DCM, THF, Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.