Description

3-Fluoro-4-(Methylsulfonyl)Phenylboronic Acid is a high-purity boronic acid derivative serving as a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly in developing active pharmaceutical ingredients (APIs) and functional organic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those containing the 3-fluoro-4-(methylsulfonyl)phenyl pharmacophore.
• Suzuki-Miyaura Cross-Coupling: A versatile reagent for palladium-catalyzed coupling reactions to create biaryl structures, a common motif in medicinal chemistry.
• Agrochemical Research: Used in the development of new herbicides and pesticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organoboron catalysts.
• Material Science: Building block for organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	3-Fluoro-4-(Methylsulfonyl)Phenylboronic Acid
CAS No.	648904-83-0
Molecular Formula	C7H8BFO4S
Molecular Weight	218.01 g/mol
Synonyms	(3-Fluoro-4-(methylsulfonyl)phenyl)boronic acid; 3-Fluoro-4-methanesulfonylbenzeneboronic acid; 4-Borono-2-fluoro-1-(methylsulfonyl)benzene; B-[3-Fluoro-4-(methylsulfonyl)phenyl]boronic acid; 648904-83-0; 3-Fluoro-4-methylsulfonylphenylboronic acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(Methylsulfonyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.