Description

Bapineuzumab CAS NO 648895-38-9 is a humanized monoclonal antibody designed to target and neutralize β-amyloid peptides. This compound is of significant interest for its potential role in addressing neurodegenerative pathologies. It is primarily utilized in advanced pharmaceutical research and development, particularly for therapeutic applications in the field of neurology.

Application

• Primary Pharmaceutical Research: Investigational therapeutic agent for Alzheimer's disease and related dementias.
• Clinical Trial Material: Serves as a critical active pharmaceutical ingredient (API) in Phase I-IV clinical studies.
• Biomedical Research: Used as a tool compound in neuroscience to study amyloid-beta plaque formation and clearance mechanisms.
• Drug Discovery & Development: Key component in preclinical and formulation studies for next-generation neurotherapeutics.
• Reference Standard: Acts as a high-purity standard for analytical method development and validation in bioanalytical laboratories.

Basic Information

Product Name	Bapineuzumab
CAS No.	648895-38-9
Molecular Formula	Contact for details
Molecular Weight	Approx. 150 kDa (Contact for details)
Synonyms	AAB-001; Anti-Amyloid Beta Monoclonal Antibody; hE8; Humanized 3D6; Anti-ABeta Antibody; Bapineuzumab (USAN/INN); Monoclonal Antibody AAB-001; Anti-Amyloid-β Antibody
EINECS	Contact for details

Quality Control

Our Bapineuzumab is manufactured under strict quality systems suitable for research and pharmaceutical development. Each batch undergoes rigorous analytical testing to ensure identity, purity, potency, and safety. Certificates of Analysis (COA) documenting compliance with relevant specifications are available upon request. Quality standards are aligned with ICH guidelines for biopharmaceuticals.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). For short-term use, aliquots may be stored at 2-8°C. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Identification (HPLC/MS)	Conforms to reference standard
Purity (SDS-PAGE)	> 95%
Assay (HPLC)	> 98.0%
Protein Content	As per COA
Endotoxin	< 1.0 EU/mg
Sterility (where applicable)	Sterile
Biological Activity (Binding Assay)	Conforms to reference

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.