Description

Oxazole, 2,2'-[(Phenylphosphinidene)Di-2,1-Phenylene]Bis[4-(1,1-Dimethylethyl)-4,5-Dihydro-, (4S,4'S)- (9Ci) is a sophisticated chiral organophosphorus-oxazole hybrid compound, serving as a high-value ligand or catalyst precursor in advanced synthetic chemistry. Its core value lies in enabling highly selective transformations, particularly in asymmetric catalysis, which is critical for producing enantiomerically pure pharmaceuticals and fine chemicals. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel synthetic routes with superior stereocontrol.

Application

• As a chiral ligand in transition metal-catalyzed asymmetric reactions, such as hydrogenation, cross-coupling, and C-H activation.
• Precursor for the synthesis of specialized organocatalysts used in the production of enantiomerically pure active pharmaceutical ingredients (APIs).
• Key intermediate in the development of novel materials with potential applications in organic electronics or sensors.
• Building block for advanced chemical research in academic and industrial laboratories exploring new catalytic systems.
• Use in methodology development for constructing complex molecular architectures with precise stereochemistry.

Basic Information

Item	Details
Product Name	Oxazole, 2,2'-[(Phenylphosphinidene)Di-2,1-Phenylene]Bis[4-(1,1-Dimethylethyl)-4,5-Dihydro-, (4S,4'S)- (9Ci)
CAS No.	642491-11-0
Molecular Formula	C41H45N2O2P
Molecular Weight	628.79 g/mol
Synonyms	(4S,4'S)-2,2'-(Phenylphosphinidenedi-2,1-phenylene)bis[4-(tert-butyl)-4,5-dihydrooxazole]; (S,S)-2,2'-(Phenylphosphinidenedi-2,1-phenylene)bis[4-(tert-butyl)-4,5-dihydrooxazole]; Chiral Phosphino-Oxazoline Ligand; PHOX Ligand Derivative; tert-Butyl-PHOX Derivative; (S,S)-t-Bu-PHOX; Asymmetric Catalyst Ligand; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of our chiral chemicals is produced and tested under strict quality management protocols to ensure identity, purity, and enantiomeric excess meet the exacting standards required for research and development. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (HPLC), chiral purity, and impurity profiles. Our commitment to traceability and consistency supports your critical synthetic workflows.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.