Description

Ethyl 3-(Trifluoromethoxy)Benzoylformate is a high-purity, specialized organic ester building block. This compound is valued for its unique trifluoromethoxy-substituted benzoylformate structure, which imparts specific electronic and steric properties critical for advanced synthesis. It serves as a key intermediate for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of complex drug candidates, especially those requiring the trifluoromethoxy pharmacophore for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethoxy group can improve activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of novel organic electronic materials and specialty polymers.
• Custom Synthesis and Contract Manufacturing: A key starting material for fine chemical producers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	Ethyl 3-(Trifluoromethoxy)Benzoylformate
CAS No.	642447-55-0
Molecular Formula	C11H9F3O4
Molecular Weight	262.18 g/mol
Synonyms	Ethyl 3-(Trifluoromethoxy)benzoylformate; Ethyl α-oxo[3-(trifluoromethoxy)phenyl]acetate; 3-(Trifluoromethoxy)benzoylformic Acid Ethyl Ester; Ethyl 2-oxo-2-[3-(trifluoromethoxy)phenyl]acetate; Benzeneacetic acid, α-oxo-3-(trifluoromethoxy)-, ethyl ester; Ethyl (3-trifluoromethoxybenzoyl)formate
EINECS	Contact for details

Quality Control

Every batch of Ethyl 3-(Trifluoromethoxy)Benzoylformate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing to ensure compliance with exacting purity standards suitable for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically by HPLC), and impurity profiles is provided with each shipment to guarantee supply reliability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.