Description

5-(4-Fluorophenyl)Isoxazole-3-Methanol is a high-purity fluorinated isoxazole derivative, a key building block in advanced organic synthesis. This compound is valued for its unique heterocyclic structure, which serves as a versatile scaffold for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Research: Used as a core structure for developing new generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated isoxazole moiety.
• Material Science: Serves as a monomer or functional additive in the research of advanced polymers and liquid crystals, where the fluorine atom can modify material properties.
• Chemical Biology & Proteomics: Employed as a tagged molecular probe or a linker in the development of chemical tools for studying biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific fluorinated heterocycles.

Basic Information

Product Name	5-(4-Fluorophenyl)Isoxazole-3-Methanol
CAS No.	640291-97-0
Molecular Formula	C10H8FNO2
Molecular Weight	193.17 g/mol
Synonyms	3-(Hydroxymethyl)-5-(4-fluorophenyl)isoxazole; 5-(4-Fluorophenyl)-3-isoxazolemethanol; (5-(4-Fluorophenyl)isoxazol-3-yl)methanol; 4-Fluoro-α-(3-isoxazolyl)benzenemethanol; 640291-97-0; 5-(p-Fluorophenyl)isoxazole-3-methanol
EINECS	Contact for details

Quality Control

Every batch of 5-(4-Fluorophenyl)Isoxazole-3-Methanol is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.