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Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine, 2,6-Dibromo-N,n-Bis[(1R)-1-Phenylethyl]-, (11Bs)- (9Ci) CAS NO 638990-02-0


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CAS No.:638990-02-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine, 2,6-Dibromo-N,n-Bis[(1R)-1-Phenylethyl]-, (11Bs)- (9Ci) is a sophisticated chiral organophosphorus compound featuring a dibrominated dinaphthodioxaphosphepin core. This molecule is of significant value as a highly specialized ligand or catalyst precursor in asymmetric synthesis, where its rigid, sterically demanding structure enables precise stereochemical control. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers developing novel active ingredients and advanced materials.

Application

  • Asymmetric Catalysis: Serving as a chiral ligand or precursor for transition metal catalysts in enantioselective C-C and C-X bond-forming reactions.
  • Pharmaceutical Intermediate Synthesis: A key building block in the research and development of novel, stereochemically complex drug candidates.
  • Advanced Material Research: Potential use in the development of chiral polymers or frameworks with specific optical or electronic properties.
  • Methodology Development: Employed by academic and industrial chemists to explore new catalytic transformations and synthetic pathways.
  • Process Chemistry Optimization: Used to develop and scale up efficient, stereoselective manufacturing routes for high-value fine chemicals.

Basic Information

Product Name Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Amine, 2,6-Dibromo-N,n-Bis[(1R)-1-Phenylethyl]-, (11Bs)- (9Ci)
CAS No. 638990-02-0
Molecular Formula C34H27Br2NO2P
Molecular Weight 681.37 g/mol
Synonyms (11bS)-2,6-Dibromo-N,N-bis[(1R)-1-phenylethyl]dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine; (S)-2,6-Dibromo-N,N-bis((R)-1-phenylethyl)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine; Chiral Dinaphthodioxaphosphepin Ligand; Br2-BINAP(O) Derivative; Asymmetric Phosphoramidite Ligand Analog; 638990-02-0
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Quality Control

Every batch of our chiral organophosphorus compounds is produced and tested under strict quality management protocols. We employ advanced analytical techniques including HPLC, NMR, and chiral analysis to ensure identity, purity, and enantiomeric excess meet exacting standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a dry, cool environment to prevent oxidation and moisture absorption. Allow the sealed container to reach room temperature before opening to minimize condensation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Enantiomeric Excess (Chiral HPLC) ≥ 99.0%
Loss on Drying ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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