Description

n-(5-Bromo-6-Methyl-2-Pyridinyl)-2-Fluorobenzamide is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 638141-77-2. This compound is valued for its precise molecular architecture, which makes it a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

This specialized intermediate serves as a key precursor in several high-value chemical synthesis pathways. Its primary applications include:

• Pharmaceutical Intermediate: A crucial building block for the research and development of new drug candidates, particularly in kinase inhibitor programs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes for potential APIs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Chemical Reference Standard: Can be utilized as an analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	n-(5-Bromo-6-Methyl-2-Pyridinyl)-2-Fluorobenzamide
CAS No.	638141-77-2
Molecular Formula	C13H10BrFN2O
Molecular Weight	309.14 g/mol
Synonyms	2-Fluoro-N-(5-bromo-6-methylpyridin-2-yl)benzamide; 2-Fluoro-N-(5-bromo-6-methyl-2-pyridinyl)benzamide; 5-Bromo-6-methyl-N-(2-fluorobenzoyl)pyridin-2-amine; Benzamide, N-(5-bromo-6-methyl-2-pyridinyl)-2-fluoro-; 638141-77-2
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for this intermediate, ensuring batch-to-batch consistency and high purity suitable for research and development applications. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.