Description

3-Oxazolidineacetonitrile,5-(Hydroxymethyl)-2-Oxo-,(5S)-(9Ci) is a high-purity, chiral oxazolidinone derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of novel pharmaceutical intermediates and fine chemicals. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors, where precise stereochemistry and functional group compatibility are paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly those targeting infectious diseases and central nervous system disorders.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in stereoselective reactions to construct molecules with high enantiomeric purity.
• Agrochemical Research: Used in the development of novel, biologically active compounds for crop protection and pest management.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes to study enzyme mechanisms and biological pathways.
• Fine Chemical Production: Integral in the multi-step synthesis of specialty chemicals requiring the oxazolidinone moiety.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry laboratories and process chemistry research.

Basic Information

Product Name	3-Oxazolidineacetonitrile,5-(Hydroxymethyl)-2-Oxo-,(5S)-(9Ci)
CAS No.	637343-77-2
Molecular Formula	C6H8N2O3
Molecular Weight	156.14 g/mol
Synonyms	(5S)-5-(Hydroxymethyl)-2-oxo-3-oxazolidineacetonitrile; (5S)-5-(Hydroxymethyl)-2-oxo-1,3-oxazolidine-3-acetonitrile; 3-Oxazolidineacetonitrile, 5-(hydroxymethyl)-2-oxo-, (5S)-; (S)-5-(Hydroxymethyl)-2-oxooxazolidine-3-acetonitrile; Chiral Oxazolidinone Acetonitrile Derivative; (5S)-5-(Hydroxymethyl)-2-oxooxazolidine-3-acetonitrile
EINECS	Contact for details

Quality Control

Our 3-Oxazolidineacetonitrile,5-(Hydroxymethyl)-2-Oxo-,(5S)-(9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive analytical data, including HPLC for assay and chiral purity, and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.