Description

2-[4-(3,4-Dichlorophenyl)-1,3-Thiazol-2-Yl]Acetonitrile is a high-purity, advanced pharmaceutical intermediate with a distinct thiazole-acetonitrile core structure. This compound is valued for its role as a critical building block in the synthesis of complex, biologically active molecules, offering precise chemical functionality for downstream derivatization. It is primarily required by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Serves as a core scaffold for developing new generations of herbicides and fungicides with enhanced efficacy.
• Chemical Biology Probe Development: Used to create tool compounds for studying enzyme mechanisms and protein-ligand interactions in life science research.
• Material Science: Potential monomer or additive for creating specialized polymers with unique electronic or thermal properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production of client-specific molecules.

Basic Information

Product Name	2-[4-(3,4-Dichlorophenyl)-1,3-Thiazol-2-Yl]Acetonitrile
CAS No.	637015-80-6
Molecular Formula	C11H6Cl2N2S
Molecular Weight	269.15 g/mol
Synonyms	2-(4-(3,4-Dichlorophenyl)thiazol-2-yl)acetonitrile; (4-(3,4-Dichlorophenyl)-1,3-thiazol-2-yl)acetonitrile; 2-(4-(3,4-Dichlorophenyl)-1,3-thiazol-2-yl)ethanenitrile; 637015-80-6; Acetonitrile, 2-[4-(3,4-dichlorophenyl)-2-thiazolyl]-
EINECS	Contact for details

Quality Control

Our production of 2-[4-(3,4-Dichlorophenyl)-1,3-Thiazol-2-Yl]Acetonitrile adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality management system supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliable supply for critical research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.