Description

1-(11Br)-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Yl-Piperidine is a sophisticated organophosphorus compound featuring a unique dinaphthodioxaphosphepin core structure. This compound is of significant interest as a specialized ligand or catalyst precursor in advanced synthetic chemistry, particularly for facilitating challenging cross-coupling and asymmetric transformations. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel active ingredients and high-value intermediates.

Application

• Catalyst Ligand in Cross-Coupling Reactions: Serves as a key component in palladium- or nickel-catalyzed reactions (e.g., Suzuki, Negishi, Buchwald-Hartwig) for constructing complex biaryl systems.
• Precursor for Asymmetric Catalysis: Used in the synthesis of chiral phosphine ligands for enantioselective hydrogenation and C-C bond formation.
• Pharmaceutical Intermediate: Acts as a building block in the research and development of new drug candidates, especially those targeting central nervous system (CNS) disorders.
• Material Science Research: Investigated for the development of novel organic electronic materials and metal-organic frameworks (MOFs) due to its rigid, conjugated structure.
• Agrochemical Synthesis: Employed in the creation of advanced, high-performance active ingredients with specific stereochemical requirements.

Basic Information

Item	Detail
Product Name	1-(11Br)-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Yl-Piperidine
CAS No.	636559-55-2
Molecular Formula	C25H19BrNO2P
Molecular Weight	476.30 g/mol
Synonyms	1-(11-Bromo)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-ylpiperidine; 4-Piperidin-1-yl-11-bromodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin; 11-Bromo-4-(piperidin-1-yl)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin; Bromo-DPPPi; (11-Br)DPPPi; Ligand precursor 636559-55-2
EINECS	Contact for details

Quality Control

Our production of 1-(11Br)-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Yl-Piperidine adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.