Description

3,5-Dibromo-L-Phenylalanine is a halogenated derivative of the essential amino acid L-phenylalanine, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in the introduction of bromine atoms at the 3 and 5 positions of the aromatic ring, which significantly alters electronic properties and provides versatile sites for further functionalization. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel bioactive molecules, including peptide-based therapeutics, enzyme inhibitors, and diagnostic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in peptide and peptidomimetic drug discovery.
• Biochemical Research: Used in proteomics and enzymology studies to investigate enzyme-substrate interactions, protein structure, and metabolic pathways involving modified amino acids.
• Peptide Synthesis: Incorporated into custom peptides to study the effects of halogenation on peptide stability, receptor binding affinity, and biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Diagnostic Agent Precursor: Potential use in the synthesis of radiolabeled compounds or contrast agents for medical imaging techniques.
• Material Science Research: Explored as a monomer or functional additive for designing novel polymers with specific optical or electronic properties.

Basic Information

Product Name	3,5-Dibromo-L-Phenylalanine
CAS No.	634917-08-1
Molecular Formula	C9H9Br2NO2
Molecular Weight	322.98 g/mol
Synonyms	(2S)-2-Amino-3-(3,5-dibromophenyl)propanoic acid; L-3,5-Dibromophenylalanine; H-3,5-DiBr-Phe-OH; 3,5-Dibromo-DL-phenylalanine (racemic mixture); 3,5-Dibromophenylalanine; 3,5-Dibromo-α-aminohydrocinnamic acid; 3,5-Dibromobenzenealanine; 3,5-Dibromo-L-Phe
EINECS	Contact for details

Quality Control

Our 3,5-Dibromo-L-Phenylalanine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high chemical purity and chiral integrity, meeting the exacting standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product may be hygroscopic; therefore, it should be kept under an inert atmosphere or in a desiccated environment for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.