Description

6-Fluoro-5-Indazolecarboxylic Acid Methyl Ester is a high-purity fluorinated indazole derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in enabling the efficient construction of complex molecular scaffolds, particularly for active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate the 6-fluoro-5-indazole motif into novel compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that leverage the biological activity of the fluorinated indazole core.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating molecular probes and tool compounds to study biological pathways.
• Material Science Precursor: Potential intermediate for the synthesis of specialty polymers, liquid crystals, or organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client projects.

Basic Information

Product Name	6-Fluoro-5-Indazolecarboxylic Acid Methyl Ester
CAS No.	633327-39-6
Molecular Formula	C9H7FN2O2
Molecular Weight	194.16 g/mol
Synonyms	Methyl 6-Fluoro-1H-indazole-5-carboxylate; 6-Fluoro-1H-indazole-5-carboxylic acid methyl ester; 1H-Indazole-5-carboxylic acid, 6-fluoro-, methyl ester; Methyl 6-fluoro-5-indazolecarboxylate; 6-Fluoro-5-(methoxycarbonyl)-1H-indazole
EINECS	Contact for details

Quality Control

Our 6-Fluoro-5-Indazolecarboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications requiring high-purity intermediates under cGMP or ISO 9001 standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.