Description

2-Chloro-6-(Trifluoromethyl)Phenylacetonitrile is a versatile and high-value fluorinated aromatic nitrile building block. This compound is critical for the synthesis of advanced agrochemicals and pharmaceuticals due to its unique trifluoromethyl and chloro substituents, which impart desirable biological activity and metabolic stability. It is primarily sought after by research and development chemists and process engineers in the fine chemical, agrochemical, and pharmaceutical industries for creating novel active ingredients and intermediates.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Pharmaceutical Building Block: Used in medicinal chemistry for the research and development of active pharmaceutical ingredients (APIs), particularly in areas requiring fluorinated motifs for improved potency and pharmacokinetics.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating specialized ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of advanced organic materials, including liquid crystals and polymers with specific electronic properties.
• Custom Synthesis and Contract Manufacturing: A valuable substrate for custom chemical synthesis services catering to R&D and pilot-scale production needs.

Basic Information

Product Name	2-Chloro-6-(Trifluoromethyl)Phenylacetonitrile
CAS No.	633317-69-8
Molecular Formula	C9H5ClF3N
Molecular Weight	219.59 g/mol
Synonyms	2-Chloro-α-(trifluoromethyl)benzeneacetonitrile; (2-Chloro-6-(trifluoromethyl)phenyl)acetonitrile; α-Chloro-α,α,α-trifluoro-o-tolunitrile (related); 2-Chloro-6-trifluoromethylbenzyl cyanide; o-Chloro-α-(trifluoromethyl)phenylacetonitrile; 2-Chloro-α-(trifluoromethyl)benzenecetonitrile; Benzeneacetonitrile, 2-chloro-α-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-6-(Trifluoromethyl)Phenylacetonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including GC, HPLC, NMR, and MS to confirm identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.