Description

Boc-β-Methyl-Dl-Phenylalanine is a protected, non-natural amino acid derivative featuring a tert-butoxycarbonyl (Boc) protecting group and a β-methyl modification on the phenylalanine backbone. This compound is a crucial chiral building block and intermediate in advanced organic synthesis, particularly for the development of novel peptides and peptidomimetics. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, drug discovery, and the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, including protease inhibitors and receptor modulators.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate modified phenylalanine residues, enabling the study of structure-activity relationships (SAR).
• Peptidomimetic Design: Essential for creating peptide analogs with enhanced metabolic stability, bioavailability, and receptor selectivity.
• Chemical Biology Research: Employed as a tool compound to probe enzyme mechanisms and protein-protein interactions.
• Academic & Industrial R&D: A valuable reagent for synthetic organic chemists in universities, CROs (Contract Research Organizations), and CDMOs (Contract Development and Manufacturing Organizations).

Basic Information

Product Name	Boc-β-Methyl-Dl-Phenylalanine
CAS No.	630424-76-9
Molecular Formula	C16H23NO4
Molecular Weight	293.36 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-3-methyl-3-phenylalanine; Boc-β-Me-DL-Phe-OH; (RS)-2-[(tert-Butoxycarbonyl)amino]-3-methyl-3-phenylpropanoic acid; tert-Butyl (1-carboxy-2-methyl-2-phenylethyl)carbamate; DL-3-Methyl-N-Boc-phenylalanine; Boc-DL-β-methylphenylalanine; N-Boc-3-methyl-3-phenylalanine
EINECS	Contact for details

Quality Control

Our Boc-β-Methyl-Dl-Phenylalanine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific results for purity, chiral purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	DL-mixture (Racemic)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.