Description

Boc-(2S,3S)-2-Amino-3-Ethoxybutanoic Acid is a high-purity, non-natural amino acid derivative featuring a tert-butoxycarbonyl (Boc) protecting group on the amine and an ethoxy side chain. This compound is a critical chiral building block for the synthesis of complex peptides and peptidomimetics, offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery and development, particularly for creating novel therapeutic agents and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for peptide-based drugs.
• Peptide Synthesis: Serves as a protected amino acid building block in solid-phase and solution-phase peptide synthesis (SPPS) to construct peptides with specific secondary structures.
• Protease Inhibitor Development: Used in the design and synthesis of inhibitors targeting specific proteases, leveraging its unique ethoxy-substituted side chain.
• Chemical Biology Research: Employed in the study of protein-protein interactions and enzyme mechanisms by incorporating it into probe molecules.
• Material Science: Potential use in the development of specialized polymers and biomaterials with tailored properties.

Basic Information

Product Name	Boc-(2S,3S)-2-Amino-3-Ethoxybutanoic Acid
CAS No.	630422-53-6
Molecular Formula	C11H21NO5
Molecular Weight	247.29 g/mol
Synonyms	(2S,3S)-2-[(tert-Butoxycarbonyl)amino]-3-ethoxybutanoic Acid; (2S,3S)-3-Ethoxy-2-((tert-butoxycarbonyl)amino)butanoic Acid; Boc-L-threonine(3-O-ethyl); Boc-Thr(OEt)-OH; N-Boc-O-ethyl-L-threonine; N-(tert-Butoxycarbonyl)-O-ethyl-L-threonine; (2S,3S)-2-(Boc-amino)-3-ethoxybutyric Acid
EINECS	Contact for details

Quality Control

Our Boc-(2S,3S)-2-Amino-3-Ethoxybutanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity research and pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >98%), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider storage under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.