Description

1-Diphenylphosphino-2-(N,n-Dimethylamino)-1H-Indene is a sophisticated, air-sensitive organophosphorus ligand with a unique indene backbone. This compound is valued for its ability to form highly active and selective catalysts, particularly in asymmetric synthesis and cross-coupling reactions. It is an essential reagent for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• As a key ligand in asymmetric hydrogenation and other transition metal-catalyzed reactions for chiral molecule synthesis.
• In the development of high-performance catalysts for C-C and C-X (X = N, O, P) cross-coupling reactions (e.g., Suzuki, Heck).
• For academic and industrial research in novel catalytic systems and mechanistic studies.
• In the synthesis of active pharmaceutical ingredients (APIs) and complex natural products requiring high enantiomeric purity.
• As a specialty chemical intermediate in the development of new organometallic complexes and materials.
• For process chemistry optimization in fine chemical and agrochemical manufacturing.

Basic Information

Item	Detail
Product Name	1-Diphenylphosphino-2-(N,n-Dimethylamino)-1H-Indene
CAS No.	628323-64-8
Molecular Formula	C23H22NP
Molecular Weight	343.40 g/mol
Synonyms	1-Diphenylphosphino-2-(dimethylamino)indene; 2-(Dimethylamino)-1-diphenylphosphino-1H-indene; (2-(Dimethylamino)-1H-inden-1-yl)diphenylphosphine; DPPAI; Indene-based P,N-ligand; Josiphos-type ligand analog; Asymmetric hydrogenation ligand
EINECS	Contact for details

Quality Control

Every batch of 1-Diphenylphosphino-2-(N,n-Dimethylamino)-1H-Indene is produced and analyzed under strict quality management protocols. We ensure high purity and consistency through advanced analytical techniques, including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C or as specified on the label. The material is easily oxidized and moisture-sensitive; ensure containers are sealed immediately after use and handled in a controlled, dry environment.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.