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1-(11Bs)-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Yl- Pyrrolidine CAS NO 627528-96-5
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CAS No.:627528-96-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1-(11Bs)-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Yl- Pyrrolidine is a sophisticated chiral organophosphorus compound, valued for its role as a ligand or catalyst precursor in advanced synthetic chemistry. Its complex, rigid dinaphthodioxaphosphepin backbone provides exceptional stereocontrol, making it a critical tool for researchers and process chemists. This high-purity specialty chemical is essential for the development of novel pharmaceuticals, agrochemicals, and materials where precise asymmetric induction is required.
Application
- Asymmetric Catalysis: As a chiral ligand for transition metal-catalyzed reactions, including hydrogenation, cross-coupling, and C-H functionalization.
- Pharmaceutical Intermediate Synthesis: Enabling the stereoselective construction of complex active pharmaceutical ingredients (APIs) and drug candidates.
- Agrochemical Research: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
- Material Science: Potential application in the synthesis of chiral polymers or as a building block for advanced organic frameworks.
- Academic & Industrial R&D: A key reagent for methodological development in organic synthesis and catalysis studies.
Basic Information
| Product Name | 1-(11Bs)-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Yl- Pyrrolidine |
| CAS No. | 627528-96-5 |
| Molecular Formula | C24H20NO2P |
| Molecular Weight | 385.40 g/mol |
| Synonyms | (11bS)-4-(Pyrrolidin-1-yl)-4H-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine; (S)-4-(Pyrrolidino)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin; (S)-DINAP-Pyrrolidine; (S)-4-Pyrrolidino-DINAP; (S)-4-(1-Pyrrolidinyl)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin; (S)-4-(Pyrrolidin-1-yl)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine; Chiral Dioxaphosphepin Ligand |
| EINECS | Contact for details |
Quality Control
Our production of 1-(11Bs)-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin-4-Yl- Pyrrolidine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. All materials are characterized by advanced analytical techniques, including NMR, HPLC, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed under an inert atmosphere to maintain stability and prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Enantiomeric Excess (Chiral HPLC) | ≥ 99.0% ee |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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