Description

3-Amino-4-(2-Dimethylaminomethyl-Phenylsulfanyl)-Benzonitrile is a high-purity, advanced pharmaceutical intermediate featuring a unique benzonitrile core substituted with amino and dimethylaminomethyl phenylsulfanyl groups. This compound is critical for the synthesis of complex bioactive molecules, particularly in medicinal chemistry research and development. It serves as a key building block for pharmaceutical companies and research institutions engaged in developing novel therapeutic agents, especially within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Kinase Inhibitor Development: Serves as a core structural component in the research and synthesis of potential kinase inhibitor candidates.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying specific biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Employed in university and institutional labs for advanced organic synthesis and methodological studies.

Basic Information

Product Name	3-Amino-4-(2-Dimethylaminomethyl-Phenylsulfanyl)-Benzonitrile
CAS No.	627490-01-1
Molecular Formula	C16H17N3S
Molecular Weight	283.39 g/mol
Synonyms	3-Amino-4-[(2-[(dimethylamino)methyl]phenyl)sulfanyl]benzonitrile; 4-[(2-[(Dimethylamino)methyl]phenyl)thio]-3-aminobenzonitrile; 3-Amino-4-((2-(dimethylaminomethyl)phenyl)thio)benzonitrile; Benzonitrile, 3-amino-4-[[2-[(dimethylamino)methyl]phenyl]thio]-; CAS 627490-01-1
EINECS	Contact for details

Quality Control

Our 3-Amino-4-(2-Dimethylaminomethyl-Phenylsulfanyl)-Benzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with client specifications and supporting regulatory filings for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.