Description

(Cys47)-Hiv-1 Tat Protein (47-57) CAS NO 627079-23-6 is a synthetic peptide fragment derived from the HIV-1 Tat protein, specifically the region from residues 47 to 57 with a cysteine substitution at position 47. This peptide is a critical research tool for studying protein-protein interactions, viral replication mechanisms, and cell-penetrating peptide (CPP) behavior. It is primarily utilized by researchers and developers in pharmaceutical R&D, biotechnology, and academic institutions focused on virology, drug discovery, and novel therapeutic delivery systems.

Application

• Biochemical Research: Used as a key reagent in studies investigating the structure, function, and intracellular trafficking of the HIV-1 Tat protein.
• Cell-Penetrating Peptide (CPP) Studies: Serves as a model compound for researching the mechanisms and efficiency of cellular uptake and cargo delivery.
• Antiviral Drug Discovery: Employed in screening assays and mechanistic studies to identify and validate novel inhibitors of HIV-1 replication.
• Protein Interaction Mapping: Utilized in pull-down assays, surface plasmon resonance (SPR), and other techniques to map binding partners and interaction domains.
• Vaccine Development: Investigated as a potential component or target in vaccine research for HIV/AIDS.
• Neuroscience Research: Applied in studies exploring the neurotoxic effects and blood-brain barrier penetration associated with HIV infection.

Basic Information

Product Name	(Cys47)-Hiv-1 Tat Protein (47-57)
CAS No.	627079-23-6
Molecular Formula	C53H86N18O14S
Molecular Weight	1207.43 g/mol
Synonyms	Tat (47-57) Cys47; HIV-1 Tat Protein Fragment (47-57), Cys47 variant; H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Cys-OH; TAT (47-57) (Cys47); HIV-1 Trans-Activator of Transcription Peptide (47-57), Cys47; ARG-LYS-LYS-ARG-ARG-GLN-ARG-ARG-CYS-TYR-GLY; Cell-Penetrating Peptide Tat (47-57) analog
EINECS	Contact for details

Quality Control

Our (Cys47)-Hiv-1 Tat Protein (47-57) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a Certificate of Analysis (COA) with key parameters including purity by HPLC, amino acid analysis, and mass spectrometry confirmation. Our quality commitment supports research requiring high-purity, well-characterized peptides for reliable and reproducible results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass confirmed by ESI-MS or MALDI-TOF
Purity (HPLC)	≥ 95%
Amino Acid Analysis	Complies with theoretical composition
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.