Description

n-[2-[4-(Trifluoromethyl)Phenylethyl]-Acetamide is a specialized organic compound featuring a trifluoromethylphenyl group, a structure that imparts unique physicochemical properties critical for advanced chemical synthesis. This compound matters as a valuable pharmaceutical intermediate and research chemical, enabling the development of novel active ingredients with enhanced metabolic stability and bioavailability. It is primarily needed by R&D and production teams in the pharmaceutical, agrochemical, and advanced material sectors seeking to incorporate fluorinated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or inflammatory diseases.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the trifluoromethyl group can improve lipophilicity and biological activity.
• Liquid Crystal & OLED Material Precursor: Acts as a synthetic intermediate for fluorinated organic compounds used in electronic display technologies.
• Chemical Biology & Proteomics: Employed as a tool compound or a tag in biochemical research to study protein interactions and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom chemical synthesis services catering to specialized client projects.

Basic Information

Product Name	n-[2-[4-(Trifluoromethyl)Phenylethyl]-Acetamide
CAS No.	625128-23-6
Molecular Formula	C11H12F3NO
Molecular Weight	231.22 g/mol
Synonyms	N-[2-[4-(Trifluoromethyl)phenyl]ethyl]acetamide; 2-[4-(Trifluoromethyl)phenyl]ethylacetamide; 1-[2-[4-(Trifluoromethyl)phenyl]ethyl]ethanamide; Acetamide, N-[2-[4-(trifluoromethyl)phenyl]ethyl]-; 4-(Trifluoromethyl)phenethylacetamide; α-(4-Trifluoromethylphenyl)acetamide; TFMPEA (common abbreviation); 625128-23-6 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our n-[2-[4-(Trifluoromethyl)Phenylethyl]-Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.