Description

3-(3-Trifluoromethyl-Phenoxy)-Phenylamine is a high-purity aromatic amine derivative featuring a trifluoromethylphenoxy substituent. This compound serves as a critical advanced pharmaceutical intermediate and key building block in the synthesis of complex organic molecules. It is primarily utilized by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Serves as a building block for developing new-generation herbicides, fungicides, and insecticides, leveraging the stability imparted by the trifluoromethyl group.
• Ligand and Catalyst Development: Used in organometallic chemistry and catalysis research to create novel ligands for transition metal complexes.
• Material Science Research: Employed in the development of advanced polymers, liquid crystals, and organic electronic materials due to its aromatic and electron-withdrawing characteristics.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-(3-Trifluoromethyl-Phenoxy)-Phenylamine
CAS No.	625106-28-7
Molecular Formula	C13H10F3NO
Molecular Weight	253.22 g/mol
Synonyms	3-(3-Trifluoromethylphenoxy)aniline; 3-Amino-3'-(trifluoromethyl)diphenyl ether; 3-(3-Trifluoromethylphenoxy)benzenamine; m-(m-Trifluoromethylphenoxy)aniline; [3-(3-Trifluoromethylphenoxy)phenyl]amine; 3-(α,α,α-Trifluoro-m-tolyloxy)aniline; Aniline, 3-(3-(trifluoromethyl)phenoxy)-
EINECS	Contact for details

Quality Control

Every batch of 3-(3-Trifluoromethyl-Phenoxy)-Phenylamine is manufactured under strict quality management systems. Our products undergo rigorous quality testing including HPLC, GC, NMR, and mass spectrometry to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.