Description

(9H-Fluoren-9-Yl)Methoxy]Carbonyl Lys(Boc)-Coch2Cl is a specialized, protected amino acid derivative designed for advanced peptide synthesis. This compound matters because it provides a critical, high-purity building block for constructing complex peptides with precise control over side-chain functionality. Pharmaceutical researchers and fine chemical manufacturers need it for the development of novel therapeutic peptides, APIs, and other bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of lysine residues with orthogonal protecting groups.
• Pharmaceutical Research & Development: Used in the synthesis of peptide-based drug candidates, including hormones, enzyme inhibitors, and targeted therapeutics.
• Combinatorial Chemistry: Serves as a valuable scaffold for generating diverse peptide libraries for high-throughput screening.
• Bioconjugation: The reactive chloroacetyl (Coch2Cl) group enables site-specific conjugation to other molecules, such as proteins, polymers, or fluorescent tags.
• API Manufacturing: Employed in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) requiring protected lysine moieties.
• Academic & Institutional Research: Essential for studies in peptide chemistry, chemical biology, and medicinal chemistry.

Basic Information

Product Name	(9H-Fluoren-9-Yl)Methoxy]Carbonyl Lys(Boc)-Coch2Cl
CAS No.	625090-55-3
Molecular Formula	C27H31ClN2O6
Molecular Weight	515.00 g/mol
Synonyms	Fmoc-Lys(Boc)-Coch2Cl; Nα-Fmoc-Nε-Boc-L-lysyl-chloroacetyl; Fmoc-Lys(Boc)-chloroacetyl; Chloroacetyl-Fmoc-Lys(Boc)-OH; (9-Fluorenylmethyloxycarbonyl)-Nε-(tert-butoxycarbonyl)-L-lysyl-chloroacetic acid; Fmoc-Lys(Boc)-Chloroacetyl Residue; Fmoc-L-Lys(Boc)-Coch2Cl; Nα-(9-Fluorenylmethoxycarbonyl)-Nε-(tert-butoxycarbonyl)-L-lysine chloroacetyl ester
EINECS	Contact for details

Quality Control

Our (9H-Fluoren-9-Yl)Methoxy]Carbonyl Lys(Boc)-Coch2Cl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for pharmaceutical research and cGMP applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral integrity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.