Description

4-Fluoro-2-Methoxybenzeneboronic Acid Pinacol Ester, 96% is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and fine chemical synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl halides and this boronic ester, fundamental in constructing biaryl structures found in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate Synthesis: Used in the research and development of novel drug candidates, particularly those containing fluorinated and methoxylated aromatic systems.
• Agrochemical Active Ingredient Development: Employed in creating new herbicides, fungicides, and insecticides where the specific substitution pattern can influence biological activity.
• Ligand and Catalyst Preparation: Acts as a precursor for synthesizing specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Utilized in the development of organic electronic materials, such as those for OLEDs and semiconductors, where precise molecular structure is critical.
• Chemical Biology & Probe Development: Serves as a versatile handle for bioconjugation and the creation of molecular probes for diagnostic and research applications.

Basic Information

Product Name	4-Fluoro-2-Methoxybenzeneboronic Acid Pinacol Ester, 96%
CAS No.	624741-83-9
Molecular Formula	C₁₃H₁₈BFO₃
Molecular Weight	252.09 g/mol
Synonyms	4-Fluoro-2-methoxyphenylboronic acid pinacol ester; (4-Fluoro-2-methoxyphenyl)boronic acid pinacol ester; 2-Methoxy-4-fluorophenylboronic acid pinacol ester; 4-Fluoro-2-methoxybenzeneboronic acid, pinacol cyclic ester; Pinacol (4-Fluoro-2-methoxyphenyl)boronate; B-(4-Fluoro-2-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; CAS 624741-83-9
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Methoxybenzeneboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the specified 96% minimum assay. Certificates of Analysis (COA) with full traceability are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 96.0%
Purity (GC)	≥ 96.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.