Description

Salusin-Beta (Human) is a bioactive peptide with the CAS registry number 624735-23-5, identified as a potent regulator of cardiovascular and metabolic functions. This compound is of significant interest for research into hypertension, atherosclerosis, and related metabolic disorders due to its role in hemodynamic regulation and cell proliferation. It is primarily utilized by pharmaceutical researchers, biotechnology companies, and academic institutions engaged in cardiovascular drug discovery and metabolic disease studies.

Application

• Cardiovascular Research: Investigation of its vasoactive properties, effects on blood pressure regulation, and role in the pathogenesis of hypertension.
• Metabolic Disorder Studies: Research into its influence on insulin resistance, lipid metabolism, and potential links to diabetes and obesity.
• Atherosclerosis Research: Study of its effects on vascular smooth muscle cell proliferation, migration, and foam cell formation.
• Biomarker Development: Exploration of its potential as a diagnostic or prognostic biomarker for cardiovascular diseases.
• Drug Discovery & Preclinical Development: Serving as a reference standard, pharmacological tool, or lead compound in the development of novel therapeutics targeting G-protein-coupled receptors.
• Cell Signaling & Molecular Biology: Used in studies to elucidate intracellular signaling pathways, receptor interactions, and gene expression regulation.

Basic Information

Product Name	Salusin-Beta (Human)
CAS No.	624735-23-5
Molecular Formula	C142H226N44O41S
Molecular Weight	3165.6 g/mol
Synonyms	Salusin β; Human Salusin-Beta; TYR-ILE-PRO-ILE-PRO-THR-PRO-HIS-PRO-GLN-ALA-LYS-VAL-GLN-LEU-SER-ALA-ARG-SER-LYS; H-Tyr-Ile-Pro-Ile-Pro-Thr-Pro-His-Pro-Gln-Ala-Lys-Val-Gln-Leu-Ser-Ala-Arg-Ser-Lys-OH; Preprosalusin (130-150); Salusin Beta; Salusinβ
EINECS	Contact for details

Quality Control

Our Salusin-Beta (Human) is produced under stringent conditions to ensure the highest standards of purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and mass spectrometry for identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, peptide content, and other critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, solutions should be aliquoted to avoid repeated freeze-thaw cycles and stored at -80°C. Allow the vial to reach room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Solubility	Soluble in water, dilute acetic acid, or DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.