Description

Cyclohexanecarbonitrile, 5-Hydroxy-2,2-Dimethyl-, (1S,5R)- (9Ci) is a high-purity chiral nitrile derivative with a defined stereochemistry, serving as a critical advanced intermediate in complex organic syntheses. Its value lies in providing a structurally precise building block for the development of pharmaceuticals and specialty fine chemicals, where stereochemical control is paramount. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to introduce functionalized cyclohexane motifs with high enantiomeric purity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder drug candidates.
• Agrochemical Research: Used in the development of novel, stereoselective herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Precursor: Serves as a starting material for the synthesis of chiral ligands used in asymmetric catalysis.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural product analogs and specialty performance chemicals.
• Academic & Industrial R&D: A valuable reference standard and building block for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	Cyclohexanecarbonitrile, 5-Hydroxy-2,2-Dimethyl-, (1S,5R)- (9Ci)
CAS No.	623563-89-3
Molecular Formula	C9H15NO
Molecular Weight	153.22 g/mol
Synonyms	(1S,5R)-5-Hydroxy-2,2-dimethylcyclohexanecarbonitrile; (1S,5R)-5-Hydroxy-2,2-dimethylcyclohexanecarbonitrile (9CI); 5-Hydroxy-2,2-dimethylcyclohexanecarbonitrile, (1S,5R)-; (1S,5R)-5-Hydroxy-2,2-dimethyl-1-cyclohexanecarbonitrile; 2,2-Dimethyl-5-hydroxycyclohexanecarbonitrile, (1S,5R)-; Cyclohexanecarbonitrile, 5-hydroxy-2,2-dimethyl-, (1S,5R)-
EINECS	Contact for details

Quality Control

Our production of Cyclohexanecarbonitrile, 5-Hydroxy-2,2-Dimethyl-, (1S,5R)- (9Ci) adheres to stringent in-process controls to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is fully characterized by advanced analytical techniques including HPLC, GC, chiral analysis, and NMR to confirm identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.