Description

N4-Amino-2'-β-C-Methylcytidine is a high-purity nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and intermediate in the synthesis of novel antiviral and anticancer therapeutics. It is primarily utilized by research institutions, pharmaceutical companies, and CDMOs engaged in the development of next-generation nucleotide-based drugs, particularly for targeting RNA viruses.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of modified nucleoside analogs for antiviral and anticancer applications.
• Antiviral Drug Research: Used in the R&D of therapeutics targeting hepatitis C virus (HCV) and other RNA viruses due to its modified ribose structure.
• Nucleotide Chemistry: Serves as a specialized building block for constructing oligonucleotides with enhanced metabolic stability and binding properties.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog to investigate polymerase mechanisms and inhibition.
• Process Development: Used by contract development and manufacturing organizations (CDMOs) for scaling up the synthesis of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	N4-Amino-2'-β-C-Methylcytidine
CAS No.	622381-10-6
Molecular Formula	C10H16N4O5
Molecular Weight	272.26 g/mol
Synonyms	2'-C-Methylcytidine N4-amine; 4-Amino-1-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 2'-β-C-Methyl-N4-aminocytidine; 2'-C-Methyl-N4-aminocytidine; 4-Amino-1-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-1,2-dihydropyrimidin-2-one
EINECS	Contact for details

Quality Control

Our N4-Amino-2'-β-C-Methylcytidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.