Description

Vabicaserin is a selective serotonin 2C (5-HT2C) receptor agonist, a compound of significant interest in pharmaceutical research and development. Its mechanism of action makes it a valuable candidate for the investigation of novel therapeutic agents targeting central nervous system disorders. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those focused on neuropharmacology and psychotropic drug discovery.

Application

• Pharmaceutical R&D: Primary use as a reference standard and active pharmaceutical ingredient (API) in the development of new CNS-targeting therapeutics.
• Preclinical Studies: Utilized in animal models to study the efficacy, pharmacokinetics, and safety profile of 5-HT2C receptor modulation.
• Biochemical Research: Serves as a critical tool compound for in vitro assays investigating serotonin receptor signaling pathways and selectivity.
• Process Development: Used in the scale-up and optimization of synthetic routes for potential commercial manufacturing.
• Analytical Method Development: Acts as a pure standard for establishing and validating HPLC, LC-MS, and other analytical techniques for quality control.

Basic Information

Product Name	Vabicaserin
CAS No.	620948-93-8
Molecular Formula	C19H21FN2O2
Molecular Weight	328.38 g/mol
Synonyms	Vabicaserin; (3aR,4S,9bS)-8-(5-Fluoropyrimidin-2-yl)-2,3,3a,4,5,9b-hexahydro-1H-pyrrolo[3,2-c]quinolin-4-ol; 2-(5-Fluoropyrimidin-2-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4,8-diol (non-preferred); 5-HT2C receptor agonist; Selective serotonin 2C agonist; Pharma substance 620948-93-8.
EINECS	Contact for details

Quality Control

Our Vabicaserin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development purposes. Each lot undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your specifications and support regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.