Description

Vabicaserin CAS NO 620948-34-7 is a high-purity pharmaceutical intermediate and research chemical of significant interest in the development of novel therapeutic agents. This compound is valued for its specific biological activity and role in advanced chemical synthesis. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) for clinical research.
• Biochemical Research: Used as a reference standard or tool compound in pharmacological and neurological studies.
• Process Chemistry: Employed in route scouting and optimization for scalable manufacturing processes.
• Analytical Development: Serves as a high-purity standard for method development and validation in quality control laboratories.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for exploratory medicinal chemistry programs.

Basic Information

Product Name	Vabicaserin
CAS No.	620948-34-7
Molecular Formula	C20H23N3O2S
Molecular Weight	369.48 g/mol
Synonyms	Vabicaserin; 620948-34-7; (3aR,4S,7aR)-Hexahydro-4-[2-[4-(3-methoxyphenyl)-1-piperazinyl]ethyl]-2H-isoindole-1,3(3aH,7aH)-dione; SB-649915; 1-[2-[(3aR,4S,7aR)-1,3-Dioxo-1,3,3a,4,7,7a-hexahydro-2H-isoindol-2-yl]ethyl]-4-(3-methoxyphenyl)piperazine
EINECS	Contact for details

Quality Control

Our Vabicaserin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, IR and NMR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.