Description

n-Benzyl-n-(1,1-Dioxidotetrahydrothiophen-3-Yl)-2-Fluorobenzamide CAS NO 620555-25-1 is a high-purity, fluorinated benzamide derivative featuring a sulfone-substituted tetrahydrothiophene moiety. This compound serves as a critical pharmaceutical intermediate and advanced building block in organic synthesis, enabling the development of novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of potential drug candidates targeting neurological and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Serves as a versatile building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Protease Inhibitor Development: The structural motif is valuable for designing inhibitors targeting specific enzymes like proteases or kinases.
• Chemical Biology Probes: Used to develop molecular probes for studying biological pathways and protein functions.
• Organic Synthesis: Employed in advanced synthetic methodologies, including palladium-catalyzed cross-coupling reactions and amide bond formation.
• Agrochemical Research: Potential intermediate for developing new crop protection agents with enhanced efficacy.

Basic Information

Product Name	n-Benzyl-n-(1,1-Dioxidotetrahydrothiophen-3-Yl)-2-Fluorobenzamide
CAS No.	620555-25-1
Molecular Formula	C19H20FNO3S
Molecular Weight	361.43 g/mol
Synonyms	2-Fluoro-N-benzyl-N-(1,1-dioxido-3-thiolanyl)benzamide; N-Benzyl-N-(1,1-dioxidotetrahydro-3-thienyl)-2-fluorobenzamide; 2-Fluoro-N-(phenylmethyl)-N-(tetrahydro-3-thienyl)-1,1-dioxide-benzamide; 2-Fluorobenzoic acid N-benzyl-N-(1,1-dioxotetrahydro-3-thienyl)amide; Benzamide, N-benzyl-N-(1,1-dioxidotetrahydro-3-thienyl)-2-fluoro-; Tetrahydrothiophene-3-sulfonamide derivative; Fluorobenzamide-sulfolane derivative
EINECS	Contact for details

Quality Control

Our n-Benzyl-n-(1,1-Dioxidotetrahydrothiophen-3-Yl)-2-Fluorobenzamide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, impurity profile, and physical characteristics are provided with every shipment to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.