Description

Azithromycin C CAS NO 620169-47-3 is a key intermediate in the synthesis of the broad-spectrum macrolide antibiotic, Azithromycin. This compound is critical for ensuring the purity, efficacy, and regulatory compliance of the final active pharmaceutical ingredient (API). It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of antibiotic formulations.

Application

• Pharmaceutical Intermediate: Primary use as a high-purity building block in the multi-step synthesis of Azithromycin API.
• Reference Standard: Serves as a critical analytical standard for quality control and impurity profiling in Azithromycin production.
• Process Development: Used in research and development to optimize synthetic routes and scale-up processes for antibiotic manufacturing.
• Regulatory Filings: Essential for compiling Chemistry, Manufacturing, and Controls (CMC) documentation for drug master files (DMF) and regulatory submissions.
• Custom Synthesis: Basis for the research and development of novel macrolide derivatives and prodrugs.

Basic Information

Product Name	Azithromycin C
CAS No.	620169-47-3
Molecular Formula	C38H72N2O12
Molecular Weight	748.99 g/mol
Synonyms	9-Deoxo-9a-aza-9a-methyl-9a-homoerythromycin A; Azithromycin Impurity C; 9a-Aza-9a-methyl-9-deoxo-9a-homoerythromycin A; (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one
EINECS	Contact for details

Quality Control

Our Azithromycin C is manufactured under strict quality systems to meet the exacting standards of pharmaceutical intermediates. Each batch is tested to ensure high purity and consistent identity, with analytical methods including HPLC, IR, and NMR. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specified parameters to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.