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1-(2-Fluorophenyl)-3-(4-Fluorophenyl)-1H-Pyrazole-4-Carbaldehyde CAS NO 618098-73-0
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CAS No.:618098-73-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1-(2-Fluorophenyl)-3-(4-Fluorophenyl)-1H-Pyrazole-4-Carbaldehyde is a high-purity fluorinated pyrazole derivative, a crucial advanced intermediate in modern organic synthesis. Its value lies in its precise molecular architecture, which serves as a versatile building block for constructing complex, biologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and agrochemicals, where its difluorophenyl-substituted pyrazole core is a key pharmacophore.
Application
- Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
- Agrochemical Synthesis: Serves as a critical precursor in the manufacture of advanced pesticides and herbicides, leveraging the stability and bioactivity of the fluorinated pyrazole structure.
- Material Science Research: Used in the development of specialty chemicals and functional materials, such as organic light-emitting diodes (OLEDs) or liquid crystals.
- Chemical Biology & Proteomics: Employed as a molecular scaffold or labeling agent in probe development for studying biological pathways and protein interactions.
- Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a commercial scale.
Basic Information
| Item | Detail |
|---|---|
| Product Name | 1-(2-Fluorophenyl)-3-(4-Fluorophenyl)-1H-Pyrazole-4-Carbaldehyde |
| CAS No. | 618098-73-0 |
| Molecular Formula | C16H10F2N2O |
| Molecular Weight | 284.26 g/mol |
| Synonyms | 4-Pyrazolecarboxaldehyde, 1-(2-fluorophenyl)-3-(4-fluorophenyl)-1H-; 1-(2-Fluorophenyl)-3-(4-fluorophenyl)-1H-pyrazole-4-carboxaldehyde; 1H-Pyrazole-4-carboxaldehyde, 1-(2-fluorophenyl)-3-(4-fluorophenyl)-; 618098-73-0; 1-(2-Fluorophenyl)-3-(4-fluorophenyl)pyrazole-4-carbaldehyde |
| EINECS | Contact for details |
Quality Control
Every batch of 1-(2-Fluorophenyl)-3-(4-Fluorophenyl)-1H-Pyrazole-4-Carbaldehyde is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical and agrochemical applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (HPLC) | Retention time corresponds to reference standard |
| Identification (IR) | Spectrum matches reference |
| Assay (HPLC) | ≥ 98.0% |
| Related Substances (HPLC) | Any single impurity ≤ 0.5%; Total impurities ≤ 1.5% |
| Residual Solvents (GC) | Complies with ICH Q3C guidelines |
| Loss on Drying | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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