Description

Doxazosin Related Compound F (15 Mg) (N,N'-Bis(1,4-Benzodioxane-2-Carbonyl)Piperazine) is a high-purity reference standard critical for analytical and quality control processes in the pharmaceutical industry. This compound serves as a key impurity marker for the active pharmaceutical ingredient Doxazosin, enabling precise monitoring and validation of drug substance purity and stability. It is essential for research laboratories, quality assurance departments, and regulatory bodies requiring reliable standards for method development, validation, and compliance testing.

Application

• Pharmaceutical Impurity Profiling and Identification as a specified impurity of Doxazosin mesylate.
• Analytical Method Development and Validation for HPLC, UPLC, and LC-MS assays in quality control laboratories.
• Stability-Indicating Studies to monitor degradation pathways and establish shelf-life for Doxazosin formulations.
• Pharmacopoeial Testing and compliance with international standards (e.g., USP, EP, ICH guidelines).
• Certified Reference Material (CRM) for calibrating equipment and ensuring analytical data integrity.
• Research and Development of generic Doxazosin products, supporting regulatory filings (ANDAs).

Basic Information

Product Name	Doxazosin Related Compound F (15 Mg) (N,N'-Bis(1,4-Benzodioxane-2-Carbonyl)Piperazine)
CAS No.	617677-53-9
Molecular Formula	C24H24N2O8
Molecular Weight	468.46 g/mol
Synonyms	N,N'-Bis(1,4-benzodioxan-2-carbonyl)piperazine; Doxazosin Impurity F; Doxazosin Related Substance F; 1,4-Benzodioxane-2-carboxylic acid, 2,2'-(1-piperazinylcarbonyl)bis-; Doxazosin EP Impurity F; Doxazosin USP Related Compound F; Piperazine, 1,1'-[2,2'-(1,4-benzodioxane-2,2'-diyl)bis(oxo-2,1-ethanediyl)]bis-
EINECS	Contact for details

Quality Control

Every batch of Doxazosin Related Compound F is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC purity analysis and spectroscopic identification, to ensure compliance with pharmacopoeial standards and customer specifications. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to support your regulatory and quality documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.