Description

Benzamide, 2-(Difluoromethyl)-n-3-Thienyl- (9Ci) is a specialized heterocyclic amide compound featuring a thiophene ring and a difluoromethyl substituent, serving as a key building block in advanced organic synthesis. Its molecular architecture makes it a valuable intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of fluorine atoms is critical for modulating biological activity and metabolic stability. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to innovate new compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A crucial synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and anti-infective agents.
• Agrochemical Synthesis: Used as a building block in the production of advanced herbicides, fungicides, and insecticides, where the difluoromethyl group can improve efficacy and environmental profile.
• Material Science Research: Serves as a monomer or precursor in the synthesis of specialty polymers, liquid crystals, or organic electronic materials requiring specific fluorine-containing motifs.
• Chemical Biology & Proteomics: Can be utilized as a scaffold or labeling agent in the design of chemical probes for studying enzyme function and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	Benzamide, 2-(Difluoromethyl)-n-3-Thienyl- (9Ci)
CAS No.	616204-44-5
Molecular Formula	C12H9F2NOS
Molecular Weight	253.27 g/mol
Synonyms	2-(Difluoromethyl)-N-(thiophen-3-yl)benzamide; N-(3-Thienyl)-2-(difluoromethyl)benzamide; 3-[[2-(Difluoromethyl)benzoyl]amino]thiophene; Benzamide, N-(3-thienyl)-2-(difluoromethyl)-; 616204-44-5; 2-(Difluoromethyl)-N-thiophen-3-ylbenzamide
EINECS	Contact for details

Quality Control

Our Benzamide, 2-(Difluoromethyl)-n-3-Thienyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting critical parameters such as assay purity and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.