Description

4-Hydroxycinnamic Acid (L-Phenylalanine Methyl Ester) Amide is a specialized amide derivative combining the structural motifs of cinnamic acid and the amino acid phenylalanine. This compound matters as a versatile chiral building block and intermediate for the synthesis of more complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients or advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly those targeting neurological or metabolic pathways.
• Peptidomimetics Research: Used in the design and synthesis of peptide analogs and mimetics to enhance stability, bioavailability, or receptor binding affinity.
• Fine Chemical Synthesis: Acts as a building block for the production of advanced organic compounds, including flavors, fragrances, and functional polymers.
• Bioconjugation & Probe Development: Utilized in creating labeled compounds or probes for biochemical and diagnostic applications due to its reactive amide and phenolic groups.
• Agrochemical Research: Investigated as an intermediate for developing novel plant protection agents or growth regulators.
• Academic & Institutional Research: Employed in university and institutional labs for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	4-Hydroxycinnamic Acid (L-Phenylalanine Methyl Ester) Amide
CAS No.	615264-52-3
Molecular Formula	C19H21NO4
Molecular Weight	327.38 g/mol
Synonyms	(2S)-2-[[(2E)-3-(4-Hydroxyphenyl)prop-2-enoyl]amino]-3-phenylpropanoic acid methyl ester; Methyl (2S)-2-[[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]amino]-3-phenylpropanoate; L-Phenylalanine, N-[(E)-4-hydroxycinnamoyl]-, methyl ester; N-[(E)-4-Hydroxycinnamoyl]-L-phenylalanine methyl ester; 4-Hydroxycinnamoyl-L-phenylalanine methyl ester; p-Coumaroyl-L-phenylalanine methyl ester
EINECS	Contact for details

Quality Control

Our 4-Hydroxycinnamic Acid (L-Phenylalanine Methyl Ester) Amide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and hygroscopic; therefore, containers should be kept sealed under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% (L-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.