Description

Melatonin-D7 is a stable isotope-labeled internal standard, specifically deuterated melatonin, essential for precise analytical quantification. This high-purity compound is critical for ensuring accuracy and reliability in mass spectrometry-based methods by correcting for analyte loss during sample preparation. It is primarily required by pharmaceutical R&D laboratories, clinical research organizations, and analytical testing facilities for method development and validation in pharmacokinetic and metabolic studies.

Application

• Internal Standard for LC-MS/MS and GC-MS analysis in bioanalytical method development.
• Quantification of endogenous melatonin levels in clinical and pharmacological research.
• Metabolite profiling and drug metabolism studies (DMPK) in pharmaceutical development.
• Quality control and assurance in the production of melatonin-based pharmaceuticals and supplements.
• Use in forensic and doping control analysis for accurate substance detection.
• Research into circadian rhythm disorders and sleep-related studies.

Basic Information

Product Name	Melatonin-D7
CAS No.	615251-68-8
Molecular Formula	C₁₃H₉D₇N₂O₂
Molecular Weight	239.31 g/mol
Synonyms	N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]acetamide-d7; Deuterated Melatonin; Melatonin (d7); 5-Methoxy-N-acetyltryptamine-d7; N-Acetyl-5-methoxytryptamine-d7; Circadin-d7; MLT-d7
EINECS	Contact for details

Quality Control

Our Melatonin-D7 is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment, chemical purity, and absence of interfering substances. We ensure compliance with relevant standards for analytical and research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and weighing accuracy.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.