Description

2-(Benzyloxy)-5-(Trifluoromethyl)Phenylboronic Acid is a high-value, synthetically versatile organoboron building block. This compound matters for its crucial role as a key intermediate in modern cross-coupling reactions, enabling the efficient construction of complex molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing the trifluoromethyl group for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the boronic acid moiety facilitates the creation of complex aromatic structures.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics, due to its functionalized aromatic core.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems and diagnostic applications.

Basic Information

Product Name	2-(Benzyloxy)-5-(Trifluoromethyl)Phenylboronic Acid
CAS No.	612833-41-7
Molecular Formula	C₁₄H₁₂BF₃O₃
Molecular Weight	296.05 g/mol
Synonyms	[2-(Benzyloxy)-5-(trifluoromethyl)phenyl]boronic acid; 2-Benzyloxy-5-trifluoromethylbenzeneboronic acid; 5-(Trifluoromethyl)-2-(phenylmethoxy)benzeneboronic acid; Boronic acid, B-[2-(phenylmethoxy)-5-(trifluoromethyl)phenyl]-; 2-(Benzyloxy)-5-(trifluoromethyl)benzeneboronic acid
EINECS	Contact for details

Quality Control

Our 2-(Benzyloxy)-5-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed specifications are provided for each lot to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.