Description

3-Amino-3-(2,6-Difluoro-Phenyl)-Propionic Acid is a specialized fluorinated amino acid derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in the unique structural motif combining an amino acid backbone with a difluorinated aromatic ring, enabling precise modulation of biological activity and physicochemical properties in target molecules. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the design and production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance bioavailability and environmental stability.
• Peptidomimetics & Bioactive Molecule Design: Incorporated into peptide analogs and other bioactive compounds to improve metabolic stability, binding affinity, and membrane permeability.
• Chemical Biology & Proteomics Research: Serves as a tool compound or a labeled precursor for studying enzyme mechanisms and protein interactions.
• Material Science Precursor: Potential use in the synthesis of specialized polymers and liquid crystals with unique optical or electronic properties.

Basic Information

Product Name	3-Amino-3-(2,6-Difluoro-Phenyl)-Propionic Acid
CAS No.	612532-20-4
Molecular Formula	C9H9F2NO2
Molecular Weight	201.17 g/mol
Synonyms	3-Amino-3-(2,6-difluorophenyl)propanoic acid; β-Amino-β-(2,6-difluorophenyl)propionic acid; 2,6-Difluoro-β-alanine, 3-amino- derivative; (R/S)-3-Amino-3-(2,6-difluorophenyl)propionic acid; 3-Amino-3-(2,6-difluorophenyl)propanoate; 612532-20-4; 3-(2,6-Difluorophenyl)-3-aminopropionic acid
EINECS	Contact for details

Quality Control

Our 3-Amino-3-(2,6-Difluoro-Phenyl)-Propionic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the exacting standards required for pharmaceutical R&D and scale-up. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for the grade.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee (or as specified)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.