Description

Azithromycin F is a key pharmaceutical intermediate in the synthesis of the widely used macrolide antibiotic, Azithromycin. Its primary value lies in enabling the production of high-purity final API, ensuring efficacy and safety in therapeutic applications. This compound is essential for manufacturers in the pharmaceutical industry, particularly those producing antibiotic formulations for respiratory, skin, and sexually transmitted infections. Consistent quality and reliable supply of this intermediate are critical for maintaining robust and compliant drug manufacturing processes.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the chemical synthesis of Azithromycin Active Pharmaceutical Ingredient (API).
• Antibiotic Production: Integral to the manufacturing supply chain for broad-spectrum macrolide antibiotics.
• Research & Development: Serves as a reference standard and starting material in pharmaceutical R&D for novel antibiotic derivatives and process optimization.
• GMP Manufacturing: Supplied for use in Good Manufacturing Practice (GMP) compliant facilities for regulated drug production.
• Contract Manufacturing Organizations (CMOs): Used by CMOs specializing in the production of antibiotic drugs for global markets.

Basic Information

Product Name	Azithromycin F
CAS No.	612069-26-8
Molecular Formula	C38H72N2O12
Molecular Weight	748.99 g/mol
Synonyms	9-Deoxo-9a-aza-9a-methyl-9a-homoerythromycin A; Azithromycin Impurity F; Azithromycin Related Compound F; (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one
EINECS	Contact for details

Quality Control

Our Azithromycin F is produced under strict quality management systems to meet the exacting standards of the pharmaceutical industry. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it conforms to stringent specifications for use as a pharmaceutical intermediate. Certificates of Analysis (COA) documenting all test results are provided with every shipment. We support compliance with major pharmacopoeial standards (e.g., USP, EP) and can tailor specifications to meet specific customer and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.