Description

n-Cbz-3-Hydroxybutan-1-Amine CAS NO 612065-83-5 is a protected amino alcohol derivative, serving as a crucial chiral building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules with precise stereochemistry. This intermediate is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of various drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in the preparation of modified amino acids and peptide mimetics, leveraging the protected amine and alcohol functionalities.
• Asymmetric Synthesis: Serves as a chiral auxiliary or starting material for constructing complex molecules with defined stereocenters.
• Ligand and Catalyst Development: Employed in the research and production of chiral ligands for asymmetric catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems.
• Fine Chemical Production: Acts as a building block for high-value specialty chemicals, agrochemicals, and flavors/fragrances.

Basic Information

Product Name	n-Cbz-3-Hydroxybutan-1-Amine
CAS No.	612065-83-5
Molecular Formula	C₁₂H₁₇NO₃
Molecular Weight	223.27 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-3-hydroxybutylamine; 3-Hydroxy-1-[(phenylmethoxy)carbonyl]aminobutane; N-Carbobenzoxy-3-hydroxybutylamine; N-Cbz-3-hydroxy-1-butylamine; (3-Hydroxybutyl)carbamic acid benzyl ester; Z-3-Hydroxybutylamine; CBZ-3-Hydroxybutylamine; 3-Hydroxy-N-Cbz-butan-1-amine
EINECS	Contact for details

Quality Control

Our n-Cbz-3-Hydroxybutan-1-Amine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to meet the stringent requirements of research and cGMP manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.