Description

tert-Butyl 4-(4-Carbamoylphenoxy)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. Its core value lies in its role as a critical building block for synthesizing complex bioactive molecules, enabling the development of new therapeutic agents. This compound is primarily needed by pharmaceutical R&D departments and fine chemical manufacturers engaged in the production of innovative drug candidates, particularly within the fields of oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a versatile linker or component in the construction of bifunctional molecules for targeted protein degradation.
• Kinase Inhibitor Synthesis: Used in the research and production of selective kinase inhibitors for cancer and inflammatory diseases.
• Chemical Biology & Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization programs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP and non-GMP production runs.
• Academic Research: Utilized in university and institutional labs for investigating new chemical entities and biological mechanisms.

Basic Information

Product Name	tert-Butyl 4-(4-Carbamoylphenoxy)Piperidine-1-Carboxylate
CAS No.	609781-33-1
Molecular Formula	C17H24N2O4
Molecular Weight	320.39 g/mol
Synonyms	1-Boc-4-(4-carbamoylphenoxy)piperidine; 4-(4-Carbamoylphenoxy)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(4-aminocarbonylphenoxy)-1-piperidinecarboxylate; 1-(tert-Butoxycarbonyl)-4-(4-carbamoylphenoxy)piperidine; 4-(4-Carbamoylphenoxy)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 609781-33-1; BOC-4-(4-Carbamoylphenoxy)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(4-Carbamoylphenoxy)Piperidine-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available for every batch and supplied upon request, detailing all relevant specifications and test results to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider using desiccants and storing under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.