Description

2-[(Trifluoromethyl)Thio]Ethanamine is a specialized organofluorine building block featuring a reactive amine group and a trifluoromethylthio moiety. This compound is valued for its ability to introduce the highly lipophilic and electron-withdrawing SCF3 group into target molecules, significantly altering their physicochemical properties. It is primarily sought by researchers and process chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for incorporating the SCF3 group into drug candidates, potentially enhancing metabolic stability, lipophilicity, and bioavailability.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the trifluoromethylthio group can improve activity and environmental profile.
• Material Science Precursor: Serves as a monomer or modifying agent in the development of specialty polymers and advanced materials with unique surface properties.
• Ligand and Catalyst Development: Employed in the synthesis of novel ligands for catalysis or as a functional handle in metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: An essential reagent for academic and industrial R&D focused on exploring new reactions and applications of organofluorine compounds.

Basic Information

Product Name	2-[(Trifluoromethyl)Thio]Ethanamine
CAS No.	609354-98-5
Molecular Formula	C3H6F3NS
Molecular Weight	145.15 g/mol
Synonyms	2-[(Trifluoromethyl)sulfanyl]ethan-1-amine; 2-[(Trifluoromethyl)thio]ethylamine; 2-(Trifluoromethylthio)ethylamine; Ethanamine, 2-[(trifluoromethyl)thio]-; 2-(Trifluoromethylsulfanyl)ethylamine; SCF3-CH2CH2-NH2; 2-Aminoethyl trifluoromethyl sulfide
EINECS	Contact for details

Quality Control

Our production of 2-[(Trifluoromethyl)Thio]Ethanamine adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong acids, strong bases, and oxidizing agents. Due to the presence of fluoride and amine functionalities, handle and store with appropriate precautions to avoid moisture ingress and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.