Description

(αs)-5-[(Dimethylamino)Sulfonyl]-α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-8-Hydroxy-2-Quinolinepropanoic Acid is a sophisticated, high-purity chemical building block designed for advanced research and development. This compound is critical for synthetic chemists and pharmaceutical developers working on complex molecular architectures, particularly in peptide and heterocyclic chemistry. Its primary value lies in its role as a protected amino acid derivative, enabling the synthesis of novel compounds for drug discovery and material science applications.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs) and investigational new drugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis as an Fmoc-protected amino acid analog for introducing specialized quinoline-based structures.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on creating new chemical entities with potential biological activity.
• Proteomics & Biochemistry: Can be utilized in the design and synthesis of enzyme inhibitors, fluorescent probes, or molecular tags due to its unique sulfonamide and fluorescent quinoline core.
• Material Science Precursor: Acts as a precursor for advanced organic materials, such as ligands for metal-organic frameworks (MOFs) or functional polymers.

Basic Information

Item	Details
Product Name	(αs)-5-[(Dimethylamino)Sulfonyl]-α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-8-Hydroxy-2-Quinolinepropanoic Acid
CAS No.	607708-62-3
Molecular Formula	C29H27N3O7S
Molecular Weight	561.61 g/mol
Synonyms	Fmoc-Asn(SO2NMe2)-OH (quinoline derivative); 8-Hydroxy-2-quinolinepropanoic acid, α-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-5-[(dimethylamino)sulfonyl]-, (αS)-; (S)-α-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-((dimethylamino)sulfonyl)-8-hydroxyquinoline-2-propanoic acid; 5-(N,N-Dimethylsulfamoyl)-α-Fmoc-amino-8-hydroxy-2-quinolinepropanoic acid; CAS 607708-62-3; Advanced Fmoc-amino acid building block; Specialty quinoline sulfonamide derivative.
EINECS	Contact for details

Quality Control

Our production of (αs)-5-[(Dimethylamino)Sulfonyl]-α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-8-Hydroxy-2-Quinolinepropanoic Acid adheres to stringent quality protocols suitable for research and pharmaceutical intermediate applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and MS for identity verification. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.