Description

Hexafluoroisopropyl Methyl Carbonate is a specialized fluorinated organic carbonate ester, identified by CAS No. 607382-52-5. This high-value intermediate is critical for introducing the hexafluoroisopropyl (HFIP) group, which imparts unique properties like enhanced lipophilicity, metabolic stability, and volatility to target molecules. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer drug discovery.
• Agrochemical Synthesis: Used to create advanced fluorinated pesticides and herbicides with improved efficacy and environmental profile.
• Polymer & Material Science: Serves as a monomer or modifier for producing fluorinated polycarbonates and other high-performance polymers with superior chemical and thermal resistance.
• Lithium-Ion Battery Electrolytes: Potential application as a fluorinated solvent or additive to enhance electrolyte stability and battery performance.
• Organic Synthesis Reagent: Employed as a versatile reagent for introducing the HFIP-protecting group or as a fluorinating agent in complex organic transformations.
• Surface Treatment & Coatings: Used in formulations to create hydrophobic, oleophobic, and chemically resistant surface coatings.

Basic Information

Product Name	Hexafluoroisopropyl Methyl Carbonate
CAS No.	607382-52-5
Molecular Formula	C5H4F6O3
Molecular Weight	226.08 g/mol
Synonyms	Methyl Hexafluoroisopropyl Carbonate; HFIP Methyl Carbonate; (1,1,1,3,3,3-Hexafluoro-2-propyl) Methyl Carbonate; Carbonochloridic Acid, 1,1,1,3,3,3-Hexafluoro-2-propyl Ester; Hexafluoroisopropanol Methyl Carbonate; HFIP-OCOOCH3
EINECS	Contact for details

Quality Control

Every batch of Hexafluoroisopropyl Methyl Carbonate is manufactured and tested under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles, ensuring compliance with your R&D or cGMP requirements. Our quality commitment includes traceability and lot-to-lot consistency for reliable performance in your critical syntheses.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature and sensitivity to fluoride/strong alkali, store in a cool, well-ventilated place, ideally at 2-8°C or as specified on the label. Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (20°C)	~1.55 g/cm³
Refractive Index (n20/D)	~1.300 - 1.320

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.