Description

Propanamide, n-[4-(1-Acetyl-2,3-Dihydro-1H-Indol-5-Yl)-5-Methyl-2-Thiazolyl]-2,2-Dimethyl- (9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. It is primarily needed by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the creation of new drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of new drug molecules, especially for central nervous system (CNS) or oncology targets.
• Organic Synthesis Building Block: Used in complex multi-step synthetic routes to construct novel indole- and thiazole-containing compounds.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of potential therapeutics.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for scale-up synthesis under cGMP conditions for clinical trial material production.
• Biochemical Research: Potential use as a tool compound or inhibitor in biochemical assays and pharmacological studies.

Basic Information

Product Name	Propanamide, n-[4-(1-Acetyl-2,3-Dihydro-1H-Indol-5-Yl)-5-Methyl-2-Thiazolyl]-2,2-Dimethyl- (9Ci)
CAS No.	606121-87-3
Molecular Formula	C19H23N3O2S
Molecular Weight	357.47 g/mol
Synonyms	N-[4-(1-Acetyl-2,3-dihydro-1H-indol-5-yl)-5-methyl-1,3-thiazol-2-yl]-2,2-dimethylpropanamide; 2,2-Dimethyl-N-[4-(5-methyl-1-acetyl-2,3-dihydroindol-5-yl)thiazol-2-yl]propanamide; 606121-87-3; Propanamide, N-[4-(1-acetyl-2,3-dihydro-1H-indol-5-yl)-5-methyl-2-thiazolyl]-2,2-dimethyl- (9CI); UNII-9J8C9W6V2R; 9J8C9W6V2R; SCHEMBL20106473; DTXSID60667623
EINECS	Contact for details

Quality Control

Our Propanamide, n-[4-(1-Acetyl-2,3-Dihydro-1H-Indol-5-Yl)-5-Methyl-2-Thiazolyl]-2,2-Dimethyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.