Description

1-Azabicyclo[2.2.2]Octane-3-Carbonitrile,(3S)-(9Ci) is a high-purity, stereochemically defined bicyclic nitrile compound, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its rigid, three-dimensional scaffold and functional handles, which are essential for constructing complex molecular architectures with high precision. This product is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs), agrochemicals, and sophisticated ligands for catalysis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Chiral Ligand Precursor: Used in the development of enantioselective catalysts for asymmetric synthesis.
• Agrochemical Synthesis: Intermediate for creating novel, high-efficacy pesticides and herbicides with specific stereochemical requirements.
• Academic & Industrial R&D: A valuable tool compound for methodological development in organic synthesis and medicinal chemistry.
• Material Science Research: Potential precursor for specialty polymers or functional materials requiring rigid, nitrogen-containing frameworks.

Basic Information

Product Name	1-Azabicyclo[2.2.2]Octane-3-Carbonitrile,(3S)-(9Ci)
CAS No.	604803-75-0
Molecular Formula	C8H12N2
Molecular Weight	136.20 g/mol
Synonyms	(3S)-1-Azabicyclo[2.2.2]octane-3-carbonitrile; (S)-Quinuclidine-3-carbonitrile; (S)-3-Cyanoquinuclidine; (S)-1-Azabicyclo[2.2.2]octane-3-carbonitrile; (3S)-Quinuclidine-3-carbonitrile; (S)-3-Quinuclidinecarbonitrile; (S)-Quinuclidin-3-yl cyanide; 604803-75-0
EINECS	Contact for details

Quality Control

Our 1-Azabicyclo[2.2.2]Octane-3-Carbonitrile,(3S)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically ≥97%), enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.