Description

Epoetin Zeta CAS NO 604802-70-2 is a recombinant human erythropoietin (rhEPO) used to stimulate red blood cell production. This biopharmaceutical is critical for managing anemia associated with chronic kidney disease and chemotherapy. It is essential for pharmaceutical manufacturers, contract research organizations (CROs), and biotechnology companies developing biosimilars and therapeutic formulations.

Application

• Therapeutic Agent for Anemia: Primary treatment for anemia in patients with chronic kidney disease (CKD) and cancer patients undergoing chemotherapy.
• Biosimilar Development: Key reference or active pharmaceutical ingredient (API) in the formulation and production of biosimilar erythropoiesis-stimulating agents (ESAs).
• Pharmaceutical Research: Used in preclinical and clinical studies to understand erythropoiesis and develop next-generation hematopoietic agents.
• Biopharmaceutical Manufacturing: Serves as the core API in the fill-finish process for injectable drug products.
• Hematology Studies: Utilized in laboratory research to study red blood cell production, bone marrow function, and oxygen transport mechanisms.

Basic Information

Product Name	Epoetin Zeta
CAS No.	604802-70-2
Molecular Formula	C~809~H~1301~N~229~O~240~S~5~
Molecular Weight	~30,400 Da (glycosylated)
Synonyms	Epoetin Zeta; Recombinant Human Erythropoietin Zeta; Retacrit (brand name); SB309; Erythropoiesis-Stimulating Agent Zeta; rhEPO-Zeta; EPO Zeta; Hemopoietic Growth Factor Zeta
EINECS	Contact for details

Quality Control

Our Epoetin Zeta is manufactured under strict quality systems. Each batch is subjected to a comprehensive battery of analytical tests including potency, purity, identity, and impurity profiling to ensure it meets stringent pharmacopeial standards. Certificates of Analysis (COA) documenting compliance with relevant specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at 2-8°C. Do not freeze. Keep the container in the original outer carton to ensure protection from all light exposure.

Specification

Item	Specification
Appearance	White or off-white powder or lyophilized cake
Identification (HPLC/Peptide Mapping)	Conforms to reference standard
Purity (SEC-HPLC)	≥ 98.0%
Potency (Bioassay)	90% - 125% of stated potency
Protein Content (UV)	As per COA
Related Proteins (HPLC)	Meets acceptance criteria
Endotoxin (LAL)	< 2.0 EU/mg
Residual Moisture (KF)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.