Description

1-(2',4'-Difluorophenyl)Ethylamine is a high-purity fluorinated aromatic amine building block of significant importance in advanced organic synthesis. Its unique difluorophenyl moiety offers enhanced metabolic stability and lipophilicity, making it a critical intermediate for the development of novel active pharmaceutical ingredients (APIs). This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorine atoms contribute to improved biological activity and environmental persistence.
• Ligand & Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with specific electronic or optical properties.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags and molecular probes in diagnostic and research applications.

Basic Information

Product Name	1-(2',4'-Difluorophenyl)Ethylamine
CAS No.	603951-43-5
Molecular Formula	C8H9F2N
Molecular Weight	157.16 g/mol
Synonyms	1-(2,4-Difluorophenyl)ethan-1-amine; (1-(2,4-Difluorophenyl)ethyl)amine; α-Methyl-2,4-difluorobenzylamine; 2,4-Difluoro-α-methylbenzylamine; 1-(2,4-Difluorophenyl)ethylamine; (R/S)-1-(2,4-Difluorophenyl)ethylamine; 2,4-Difluoro-α-methylbenzylamine
EINECS	Contact for details

Quality Control

Our 1-(2',4'-Difluorophenyl)Ethylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess (where applicable), and identity confirmation via FT-IR and NMR. We provide detailed Certificates of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.